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emfizz.com November 24, 2017


Reason Flu Vaccines Are So Lousy: They're Grown in Eggs

08 November 2017, 10:23 | Todd Saunders

Goldstream Gazette file

Goldstream Gazette file

For now, the vaccine has only been tested on mice. Those that received higher doses of the vaccine didn't even get sick, the report says. This is a very significant advancement over the traditional influenza vaccine platform.

"The good news is that it's much more hard to drive mutations in the stalk, but it's not impossible", said David J. Topham, Ph.D., study author and the Marie Curran Wilson and Joseph Chamberlain Wilson Professor in the department of Microbiology and Immunology at URMC. "We can protect ourselves and also our family, friends and the community", said family nurse practitioner Sarah Fincham, assistant clinical professor at Washington State University's college of nursing in Spokane.

According to estimates by the Centers for Disease Control and Prevention, 40 million Americans suffered from the flu in 2015-16, with 970,000 being hospitalized. You can have some side effects after vaccination, but this is not flu illness.

However, as the study was done on mice, more research needs to be conducted to determine if the vaccine works in human.

Weaver and a team of researchers at the university have been developing a shot that would provide life long protection against the flu.

Why the flu vaccine may not be as effective as we believe Of course, we know that flu viruses mutate, and we have seen examples of this happening, especially in bird flu viruses.

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"Every year the World Health Organization looks to outbreaks in the Southern Hemisphere to gauge which strains are circulating and how virulent they are", she said. They're far less effective when mismatched.

In general, manufacturing of flu vaccines involves the use of proteins originating from the external layer of destroyed flu viruses.

Although the flu vaccine is not flawless and some people who get vaccinated may still get the flu, it's possible that the vaccination may make symptoms milder.

Pursuit of a universal influenza vaccine has been hard. The 2016-2017 vaccine included a clade 3C.2a H3N2 strain, but the egg-adapted version of the viral strain lacked the new site.

These approaches have shown promising results.

Flu vaccines aim to protect us by priming our immune systems. Their vaccine contains "ancestral" or "consensus" flu genes from the four major flu strain types: H1, H2, H3 and H5. "Because they are centralized and represent all the strains equally, they could provide a basis for immunity against all evolved strains".



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