Mustafi was forced off in the first half of Germany's 5-1 World Cup qualifying victory over Azerbaijan on Sunday and is not expected to return until after the next worldwide break.
Wenger said in a press conference: "We lost Mustafi for four to six weeks".
Wenger has confirmed that the 25-year-old will be out for between a month and six weeks, meaning he could make his return in the north London derby against Tottenham following the final worldwide break of 2017. "We'll check him today - he has a hip problem".
"I will decide what I have to do when Koscielny has his test tomorrow. We have to cope with that now".
Though, Kolasinac will have a late fitness test this week, Wenger confirmed, as he should hopefully be okay for Arsenal's trip to Watford in the Premier League this Saturday. At the moment, he's not available. "It looks like if he survives the test he is capable to play".
Arsenal could be without seven first-team players for their clash against Watford on Saturday (14 October), which could derail their current unbeaten run in the Premier League. "Mentally, I will have to assess the situation when he comes back tomorrow".
Attack: Mesut Ozil is back in contention after recovering from a knee injury that's kept him out for the last four games so the German schemer could get a recall in attack this weekend. "He trained on his own and the first signs are positive, so we chose to give him a test tomorrow".
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