One day these little piggies could give you more than just bacon Luhan Yang Egenesis
Growing human transplant organs in pigs has become a more realistic prospect after scientists used advanced gene editing to remove threatening viruses from the animals' DNA.
While scientists had long hoped to be able to transplant animal organs to humans in need, they had always run up against the problem of so-called PERV cells.
"We now have living, healthy, four-month-old pigs that we have engineered", George Church, Professor of genetics at Harvard Medical School and adviser to eGenesis, told Fox News.
This is the first time researchers have been able to demonstrate they were able to inactivate PERV and open the way for xenotransplantation (the act of transplanting animal organs to humans) without cross-species contamination. In conjunction with a method to inhibit primary cell death during multiplex genome editing, researchers successfully produced viable PERV-free porcine embryos via somatic cell nuclear transfer, using engineered primary cells. So far the team has only made female pigs, raised in a lab. "We think the advancement of gene editing can help us address both of them", Yang said. This involves immunological changes as well as making the tissues compatible and fixing blood-clotting issues.
Disney parts with Netflix; to launch two streaming services
As for the Star Wars and Marvel lovers out there, additional streaming services for each could also be on the cards in the future. This will include films releasing in 2019 such as Toy Story 4 , the sequel to Frozen and a new, live version of The Lion King .
Chris Brown Commented on Rihanna's Sizzling Instagram Pics
It should be remembered that Brown had assaulted Rihanna the night before the 2009 Grammys which left her bloodied and bruised. Another fan tagged another of Rihanna's exes, Drake, into the fold but thankfully, he was smart enough not to get involved.
Wisconsin LB Cichy tears ACL, out for season
Cichy's spot on the inside figures to be filled by Chris Orr, who is coming off an injury that cost him nearly all of last season. He played in just three games his freshman year and eight his sophomore year because of injury before redshirting the next year.
"This is a major milestone", Church added. Researchers in the study used the gene-editing technology to effectively cut out a porcine endogenous retrovirus (PERV) commonly found throughout pig bodies. Those cells proved more fragile when subjected to CRISPR's hack job: Once edited, they failed to grow normally, possibly because the damage to their DNA prompted them to stop dividing or self-destruct, Yang says.
There were 33,600 organ transplants previous year, and 116,800 patients on waiting lists, according to Dr. David Klassen, chief medical officer at the United Network for Organ Sharing, a private, nonprofit organization that manages the nation's transplant system. If this happened, it may cause diseases like cancer.
Pig organs are the same size as human organs and function pretty much the same way but pig to human transplantation has always been an elusive goal for researchers due to fear of activating dormant viral diseases in the pig's cells. In the new work, done with a team of Danish and Chinese collaborators, the eGenesis team applied the CRISPR system to cells derived from the connective tissue of fetal pigs. Tector says his own team stopped worrying about the viruses years ago, because it is not clear whether the U.S. Food and Drug Administration will require the viruses to be removed prior to transplantation. The research is basically a "safety check", says Pablo Ross, a geneticist at the University of California, Davis, who did not take part in the study. "I fail to understand the significance of this [infectivity] unless it is shown that it can cause some kind of disease". Still, Denner says, "If it is possible to knock [PERVs] out, you should do it".
Guam keeps its cool after North Korea strike threat
A pair of B-1B USA strategic bombers flew over the Korean Peninsula in a joint drill with South Korean fighters on Tuesday. Underwood, the president of the University of Guam and the island's former delegate to the House of Representatives.
USA tensions with North Korea rattle markets
Trump tweeted Wednesday morning that one of his first orders as president was to "renovate and modernize" the nuclear arsenal. The pan-European FTSEurofirst 300 index lost 0.75 per cent and MSCI's gauge of stocks across the globe shed 0.33 per cent.
Rail boost for the West Midlands
There will be more than 180 new train carriages for the West Midlands, creating more space for people. Abellio already runs the Scot Rail and Greater Anglia rail franchises in the UK.
North Korea 'risks end of regime'
Pacific Command's Joint Intelligence Center, told CNN a single ship equipped with Aegis could probably take out two missiles. The US knows that a strike on North Korea would force the regime to retaliate against US allies South Korea and Japan.
Sushma Swaraj in Nepal, meets President
The 18th Session of the BIMSTEC senior officials' meeting kicked off in the capital on Thursday morning. The EAM said that the Indian government was looking forward to the state visit of PM Deuba to India.
Manana contacted Mbalula after beating woman
NPA spokesperson Phindi Mjonondwana said Manana had handed himself over at the Douglasdale Police Station. He says he agrees with the public that Manana should be treated as a normal citizen.