emfizz.com
emfizz.com May 26, 2017


Drug developed in Manitoba could fight antibiotic-resistant bacteria

22 April 2017, 01:29 | Jan Cross

Research on the antibiotic drug PEG-2S shows that it can offer a way to fight antibiotic resistance without damaging healthy cells

Gut bacteria

There may be a new weapon in the battle against antibiotic-resistant infections, thanks to some Manitoba scientists.

Although the threat of drug-resistant bacteria is rising, no new class of antibiotics has been approved in 30 years. Because a number of bacteria rely on the NQR pump for energy, PEG-2S could be a boon in the fight against drug-resistant bacteria.

Pseudomonas aeruginosa is often acquired by people with weakened immune systems in hospitals.

Grant Pierce, executive director of research at St. Boniface Hospital and a professor at the University of Manitoba, said that PEG-2S is created to attack bad bacteria without affecting healthy human cells. "We have not only defined a new and effective target, we have designed a drug to attack it without affecting normal cells".

"So it's a breakthrough in that it's attacking a completely different target", he said.

The research suggests the drug can target at least two of the top 10 priority pathogens listed by the World Health Organization.

RJD scoffs at Sushil Modi's allegations against Lalu, Tej Pratap
This way, the land as well as the money generated through its inflated value remained with the family. The Katyals had already separated themselves from the firm in 2014.


Epilepsy drug linked to birth defects
The regulator itself said the figures should be "interpreted with caution", according to Sanofi's statement. Medically necessary exceptions, he added, should be rare and accompanied by "mandatory contraceptive use".


Pence in Indonesia With Trade on Agenda
National Security Agency's mass surveillance, published the coup article by freelance journalist Allan Nairn earlier this week. He paved the way for a bigger US military presence in the Philippines, where American bases were shuttered 25 years ago.


Dr Pierce told a Canadian TV news channel that the antibiotic could kill bacteria that causes Legionnaires' disease, cholera, typhoid fever and bubonic plague.

It is the first antibiotic discovered since 1987.

Pierce said the development of PEG-2S is "novel and exciting", although it's still in the laboratory stage.

The two doctors have applied for patent approval from the U.S. Food and Drug Administration. They then plant to begin testing on animals and, provided those tests go well, trials on humans.

The research was published in the Canadian Journal of Physiology and Pharmacology.



Other News

Trending Now

Authorities remove more than 100 cats from MI home
The Calhoun County Sheriff's Department says the homeowner was cooperative during the investigation which is continuing. Download the WZZM 13 app now . â–ºMake it easy to keep up to date with more stories like this .

Oil prices flat in choppy trade, rising U.S. production weighs
Gasoline futures lead the losses the energy futures, with May gasoline RBK7, -3.12% down 1.2 cents, or 0.7%, at $1.699 a gallon. Last year's average barrel price was $42.84 per barrel, the report said, but this year the average should rise to $55.23.

North Korea drivers scramble as gas stations limit services
The Su Pung, which also flies a North Korean flag, was shown to be at a berth at the port's Jintang coal terminal, data showed. North Korea has conducted five nuclear tests since the early 2000s, all of which have been roundly condemned by China.

Leading Candidate in French Presidential Race
Police killed one man whom they said was armed shortly after the shooting, in which two others were severely wounded. Under French election rules, Friday was due to be the final day of campaigning before Sunday's first round of voting.

Eight JCs to merge in 2019
This is the first time that junior colleges have been merged, said a press statement from the Ministry of Education (MOE). This is why more primary schools will be built in the newer estates even as others are being merged.

Tyson Fury firmly in Anthony Joshua's thoughts after Wladimir Klitschko fight
Fury labelled Joshua a "poor man's Frank Bruno" on Twitter in a reference to the popular British heavyweight of the 1980s. Fury said: "I do think it's a tiny bit soon for Joshua , but I do wish him all the best and I hope he wins".

Pair tasered after chase in Melbourne
A wanted man has been Tasered and arrested by police after a dramatic early-morning high-speed vehicle chase on Punt Road. Police said they used a Taser and capsicum spray to arrest a man and woman at the scene.

UP govt asks for fresh technical evaluation to set up Jewar airport
The committee would meet every month and guide and facilitate close cooperation in this regard among the various stakeholders. By the end of 2017, the airside capacity is expected to rise by 10% to 72-73 aircraft movements per hour.

Stocks To Invest: Ixia (XXIA), Gramercy Property Trust, Inc. (GPT)
Gerstein Fisher maintained its position in Camden Property Trust (NYSE:CPT) during the third quarter, Holdings Channel reports. Liberty Property Trust (the Trust) is a self-administered and self-managed Maryland real estate investment trust (REIT).

Three soldiers killed by Boko Haram IED in Borno
He said troops recovered AK 47 rifles, nine rounds of ammunition and 22 rounds of North Atlantic Treaty Organisation ammunition. Enenche was holding a seminar with defence correspondents and will revert back as soon as possible.