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Drug developed in Manitoba could fight antibiotic-resistant bacteria
22 April 2017, 01:29 | Jan Cross
Research on the antibiotic drug PEG-2S shows that it can offer a way to fight antibiotic resistance without damaging healthy cells
There may be a new weapon in the battle against antibiotic-resistant infections, thanks to some Manitoba scientists.
Although the threat of drug-resistant bacteria is rising, no new class of antibiotics has been approved in 30 years. Because a number of bacteria rely on the NQR pump for energy, PEG-2S could be a boon in the fight against drug-resistant bacteria.
Pseudomonas aeruginosa is often acquired by people with weakened immune systems in hospitals.
Grant Pierce, executive director of research at St. Boniface Hospital and a professor at the University of Manitoba, said that PEG-2S is created to attack bad bacteria without affecting healthy human cells. "We have not only defined a new and effective target, we have designed a drug to attack it without affecting normal cells".
"So it's a breakthrough in that it's attacking a completely different target", he said.
The research suggests the drug can target at least two of the top 10 priority pathogens listed by the World Health Organization.
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